Lack of effect of a high polyunsaturated fat diet on the growth of transplantable colon tumors and on the cytolytic activity of macrophages in rats.

نویسندگان

  • D Reisser
  • P Lagadec
  • H Pelletier
  • C Fady
  • N O Olsson
  • J F Jeannin
چکیده

The effect of a high dietary level of polyunsaturated fat was tested on the growth of three different colon cancer cell lines injected subcutaneously into syngeneic rats. This effect was also tested on the in vitro cytolytic activity of resident peritoneal macrophages, natural or endotoxin and/or indomethacin-modulated. A 12% corn oil dietary supplement had no effect in any of the cases tested.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Aerobic Continuous Training on Myonectin, Insulin Resistance and Liver Enzymes in Rats with Nonalcoholic Fatty Liver Disease

Background. Non-alcoholic fatty liver disease, is the most common reason of liver disorders that can be controlled by dieting and regular physical activity.  Objectives. The aim of this study was to investigate the effect of aerobic continuous training on serum levels of myonectin, insulin resistance and liver enzymes in rats with non-alcoholic fatty liver disease. Methods. Thirty-four male W...

متن کامل

THE EFFECT OF 12 WEEKS OF MODERATE INTENSITY CONTINUOUS TRAINING (MICT) ON INFLAMMATORY AND ANGIOGENESIS FACTORS OF VISCERAL AND SUBCUTANEOUS ADIPOSE TISSUE IN OBESE RATS: A SEMI-EXPERIMENTAL STUDY

Background & Aims: Physical activity by modulating angiogenesis in adipose tissue, effects on the entire body metabolic profile. Therefore, the aim of this study was to investigate the effect of 12 weeks of moderate intensity continuous training on VEGF, PEDF and PAI-1 of visceral and subcutaneous adipose tissue in obese rats. Materials & Methods: 15 male Wistar rats were divided into 2 groups...

متن کامل

The Effect of Four Weeks of Aerobic Training on The Activity of Left Ventricular Catalase Enzyme And Insulin Resistance Index In Male Rats Treated With Streptozotocin And Exposed To A High-Fat Diet

Background: A high-fat diet causes hyperinsulinemia and increases insulin resistance in the body. On the other hand, the oxidative stress caused by hyperglycemia can lead to the exacerbation of hyperglycemia and increase the complications of diabetes, and cardiovascular diseases are one of the most important complications of diabetes mellitus. Therefore, the aim of this study was to investigate...

متن کامل

Biochemical and histopathological study on preventive effects of Punica granatum L. extract on fatty liver disease in the rats receiving high fat diet.

Background and Aim: Non-alcoholic fatty liver disease (NAFLD) is recognized as a metabolic liver disease in the world. The purpose of this study was to investigate the preventive effects of Punica granatum extract on fatty liver disease in the rats receiving high fat diet. Material and Methods: In this study rats were divided into 6 groups: healthy control, feeding with high fat diet, feeding ...

متن کامل

اثر نوع تمرین بر نشانگران آپوپتوز هپاتوسیتی در رت‌های تغذیه شده با غذای پرچربب

Background:Anti-inflammation and anti-apoptotic effects of physical activity have been proven and its effectiveness depends on intensity, duration and type. Since obesity is considered as a mild chronic inflammation, it is reasonable that the degenerative damages occurin tissues, especially in the liver as the center of metabolism. The aim of this study was to investigate the effect of two typ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Reproduction, nutrition, developpement

دوره 27 6  شماره 

صفحات  -

تاریخ انتشار 1987